Shake lightly. Apply serum to face AM and PM. If used as part of a NIOD regimen, apply after CAIS but before MMHC. Avoid unprotected UV exposure when using this formula. If irritation occurs, cease use and consult a physician. Use only as directed on unbroken skin. Patch testing prior to use is advised. Refer to our in-depth guide to patch testing. Keep out of reach of children.