If used as part of a NIOD regimen, apply to the neck and lower face areas in the morning and evening in this order after cleaning: CAIS, MMHC, NEC. If used as part of another skincare regimen, apply after serums but before any heavier creams. If NIOD HV is used, it should be applied after NEC. Apply to the neck and lower face areas in the AM and PM. If irritation occurs, cease use Aqua (Water), Caprylyl Methicone, Glycerin, PEG-12 Dimethicone/PPG-20 Crosspolymer, Pentaerythrityl Tetraisostearate, Butylene Glycol, Hyaluronic Acid, Ethoxydiglycol, Dimethyl Isosorbide, Polyacrylate Crosspolymer-6, Plantago Lanceolata Leaf Extract, Leontopodium Alpinum Callus Culture Extract, L-Carnitine, Caffeine, Acetyl Dipeptide-1 Cetyl Ester, Trifluoroacetyl Tripeptide-2, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-2, Acetylarginyltryptophyl Diphenylglycine, Acetyl Cyclohexapeptide-34, Urea, Adansonia Digitata Fruit Extract, Coccoloba Uvifera Fruit Extract, Lactic Acid/Glycolic Acid Copolymer, Glyceryl Caprylate, Polyvinyl Alcohol, Hippophae Rhamnoides Oil, Maltodextrin, Dextran, Trisodium Ethylenediamine Disuccinate, Caprylic/Capric Triglyceride, Hydroxyethylcellulose, Xanthan gum, Sorbitan Laurate, Stearalkonium Hectorite, Propylene Carbonate, Tocopherol, Phenylpropanol, Potassium Sorbate, Sodium Benzoate, 1,2-Hexanediol, Phenoxyethanol, Caprylyl Glycol.and consult a physician. Use only as directed on unbroken skin. Patch testing prior to use is advised. Keep out of reach of children.